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Mantle Cell Lymphoma

At medium power, one sees a monotonous proliferation of small cells. Larger forms are rare or absent.

The lymphoid nuclei are irregular. Traditionally they are described as "angulated". In fact here the degree of indentation approaches what is seen in a different type of cell, the small-cleaved cell. In the center is a histiocyte with eosinophilic, granular cytoplasm, which is characteristic of many cases of mantle cell lymphoma.

Multiple lymphomatous polyposis in the colon.

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