The Cancer Institute of New Jersey, UMDNJ-Robert Wood Johnson Medical School

David J. Foran, Ph.D. Principal Investigator.

Dr. Foran leads the PathMiner project. He is a Professor of Pathology, Laboratory Medicine & Radiology and the Director of the interdepartmental Center for Biomedical Imaging & Informatics at UMDNJ- Robert Wood Johnson Medical School and The Cancer Institute of New Jersey. He has advanced training and expertise in the areas of engineering, physics, zoology and medical imaging and pathology. He has designed and developed systems and algorithms for machine vision applications, computer-assisted diagnosis, and interactive telemedicine. Dr. Foran is responsible for quantitative imaging, database design, as well the design, development, and implementation of the pattern recognition, data fusion and query algorithms.

Lauri A. Goodell, M.D., Co-Investigator.

Dr. Goodell is the Director of the Division of Hematopathology at Robert Wood Johnson University Hospital. She is a board-certified hematopathologist with research and clinical training in surgical pathology and cytopathology. She has collaborated with Dr. Foran on several successful projects over the course of more than 10 years including the development of a computerized surgical pathology consultation service and on developing the prototype for the proposed system. Dr. Goodell is proficient with the imaging workstation, distributed telemicroscopy system, and Image Guided Decision Support system that has been utilized to collect and process images. Her role in the project is to assist in high-level design of search algorithms and to gauge the performance of the system. She plays an important role in selecting representative cases, directing immunophenotyping, providing ground-truth diagnoses, and will participate in inter-institutional prospective studies.

Gratian Salaru, M.D., Consulting Pathologist.

Dr. Salaru is board-certified in Anatomical and Clinical Pathology. He is an Instructor at UMDNJ-Robert Wood Johnson Medical School. Dr. Salaru works under the direct supervision of Dr. Foran and Dr. Goodell and assists in selecting representative cases, collecting and processing images, and providing ground-truth diagnoses. He is proficient with the imaging workstation, distributed telemicroscopy system, and the Image Guided Decision Support system. He also provides assistance and translational support for the projects currently underway at the Center for Biomedical Imaging & Informatics.

Wenjin Chen, Ph.D., Scientific Programmer.

Dr. Chen has advanced training in the pathology, molecular biology and computer science. She has been working in the Foran laboratory for nearly 9 years and has served as one of the chief developers of the software for several major projects. Dr. Chen is a Research Associate and the Associate Director of New Technology at the Center for Biomedical Imaging & Informatics. She has worked with Dr. Foran in the development of query and data fusion algorithms, in the design and development of databases and in determining a definitive set of image metrics which describe the underlying histology.

Lin Yang, M.S., Ph.D. Candidate.

Mr. Yang is a Ph.D. student in the graduate program in electrical and computer engineering in Rutgers University. He has advanced training in computer vision, image/signal processing and computer scienc. He has been working in CBII since 2004 and is one of the chief developers of the Pathminer software. As part of his thesis research he worked under the direction of Dr. Foran on different areas of computer vision, such as the development of robust image segmentation algorithms, design and development of content-based image retrieval systems, mutiple class object recognition/segmentation and machine learning algorithms for medical image/data analysis.

Vicky Chu, M.S., Database Administrator/Programmer.

Ms. Chu has advanced training in computer science and significant experience in managing scientific and clinical databases. She served as a scientific programmer and database administrator for tissue banking services at the University of Pittsburgh for nearly 5 years. She has joined the Foran laboratory in the summer of 2006 and is working under the direction of Dr. Chen and Dr. Foran in the development and maintenance of the integrity of the project's image archives and databases.

Bonnie Huang-Hall, B.S., M.D., Ph.D. Candidate.

Ms. Hall is an M.D., Ph.D candidate. She has been working on the PathMiner project since spring, 2004. As part of her thesis research she has worked under Dr. Foran on the development of the algorithms used to perform multivariate texture analysis and has demonstrated their utility in a range of pathology applications.

William Cukierski, B.S., Ph.D. Candidate.

Mr. Cukierski is a Ph.D. student in the graduate program in biomedical engineering. He has advanced training in physics. He has been working on this project since summer, 2006. As part of his thesis research, he worked under the direction of Dr. Foran on developing algorithms correlating image feature measurements with image metrics for outcome assessment and therapy planning.

Shawn Patton, M.S., Scientific Programmer.

Mr. Patton is a computer scientist with extensive experience in the areas of network-based imaging and multimedia applications. He worked under the direction of Dr. Foran in order to implement changes in algorithms during prototyping and during the development of the graphical user interface for PathMiner. In addition, he addressed routine system and network administration issues in this project.

 

University of Pennsylvania

Michael D. Feldman, M.D., Ph.D. , Co-Principal Investigator.

Dr. Feldman is board certified in Anatomic and Clinical Pathology. He has collaborated with Dr. Foran on several projects over the course of more than 5 years including the development of the distributed telemicroscopy system. He is a national leader in pathology informatics. Dr. Feldman is the Director of pathology informatics at the University of Pennsylvania School of Medicine. He is proficient with the imaging workstation that is being utilized to collect and process images and the Image Guided Decision Support system. His role on the project will be to assist in high-level evaluation of search algorithms and to gauge the performance of the system. He has also participated in inter-institutional prospective studies.

Adam Bagg, M.D. , Co-Principal Investigator.

Dr. Bagg is a board certified hematopathologist with research and clinical training in clinical pathology, hematopathology and molecular diagnostics. He is nationally recognized as an authority in hematopathology and molecular diagnosis of hematologic malignancies. Dr. Bagg directs clinical laboratory hematology services at the Hospital of the University of Pennsylvania. He played an important role in selecting representative cases, directing immunophenotyping, and providing ground-truth diagnoses. He will also participate in inter-institutional prospective studies.

 

Rutgers University

Peter Meer, D.Sc. , Co-Principal Investigator.

Dr. Peter Meer is a Professor of Electrical and Computer Engineering at the Center for Advanced Information Processing, Rutgers University. He and Dr. Foran have worked closely on several joint projects in medical imaging, telemedicine, and pattern recognition over the course of nearly ten years. Dr. Meer is responsible for robust estimation and statistical optimization of algorithms.

Bogdan Matei , Ph.D.

Mr. Matei earned his Ph.D. in computer & electrical engineering. He worked under the direction of Dr. Foran and Dr. Meer to address statistical optimization issues and assist in identifying a definitive set of image metrics. He recently accepted a position as a Research Scientist in the Imaging Division of Sarnoff Corporation in Princeton.